Systagenix Promogran Prisma Matrix Wound Dressing

Systagenix Promogran Prisma Matrix Wound Dressing

Brand/Manufacturer: ACELITY/SYSTAGENIX
  • FSA Approved

Promogran Prisma Matrix Wound Dressing is used for the management of exuding wounds. It is designed to kick start the healing process while providing protection from infection. Prisma Wound Dressing absorbs destructive components of chronic wound fluid and creates the optimal environment for cellular development. It is a simple-to-use primary dressing.

Promogran Prisma Matrix contains

  • 44% oxidized regenerated cellulose (ORC)
  • 55% collagen
  • 1% silver-ORC

Best Price Guarantee

Item # Desc Pkg Reward Price
MA123 19.1 sq. in. Each $2.10
MA123 19.1 sq. in. 10/Pack $21.93
MA123 19.1 sq. in. 40/Case $87.73
MA028 4.34 sq. in. Each $0.83
MA028 4.34 sq. in. 10/Pack $8.08
MA028 4.34 sq. in. 10/Pack, 4Pk/Case $31.18

Promogran Prisma Matrix Wound Dressing Features

  • Stimulates new tissue development by encouraging the deposition and organization of newly formed collagen fibers and granulation tissue in the wound bed
  • Collagen chemically binds to matrix metalloproteinases (MMPs) and absorbs components of wound exudate
  • Provides a biodegradable matrix for cellular invasion and capillary development
  • Acelity Promogran may be used under compression therapy with healthcare professional supervision
  • Presence of silver prevents anti-microbial activity in the wound bed promoting quicker healing time
  • This Composite Dressing can be pre-moistened to form a gel and molded to fit the wound, or it can be cut with sterile scissors to fit the wound shape
  • Prisma dressing for wounds has known haemostatic properties
  • Not necessary to remove any Promogran Prisma residue from the wound
  • Ideal for all the areas of the body
  • Can be worn for up to seven days depending on wound conditions
  • Shape: Hexagon
  • Sterile

When to use Prisma Wound Matrix Dressing?

Under the supervision of a healthcare professional, Promogran Dressing uses are for the management of:
  • Diabetic Ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular etiologies
  • Full-thickness and partial thickness wounds
  • Donor sites and other bleeding surface wounds
  • Abrasions
  • Traumatic wounds healing by secondary intention
  • Dehisced surgical wounds

Prisma Matrix Composite Dressing Contraindications

  • Patients with known sensitivity to silver, ORC or collagen
  • Third-degree burns

How Does Prisma Wound Dressing Work?

Promogran Prisma Wound Dressing consists of a freeze-dried composite of collagen, silver-ORC and oxidized regenerated cellulose (ORC).

Optimum Wound Environment:

Promogran Prisma Matrix transforms into a soft, conformable, biodegradable gel in the presence of exudate, allowing contact with all areas of the wound. A moist micro-environment is maintained at the wound surface, which is conducive to epithelialization, granulation tissue formation, and optimal wound healing.

Role Of Silver in Promogran Prisma Matrix:

Silver-ORC is said to be comprised of 25% w/w ionically bound silver, which is a well-known antimicrobial agent. Prisma dressing with silver provides an effective antimicrobial barrier that helps in reduction of bacterial development with common wound pathogens such as, Pseudomonas aeruginosa, Staphylococcus aureus, Eschericia coli, and Streptococcus pyogenes. Reduction of bacterial bioburden in the dressing may result in reduced risk of infection.

What to buy with Prisma Wound Dressing

How To Apply Promogran Prisma Dressing?

Prisma Dressing Application

There are few prior promogran dressing application instructions that needs to be follow
  • Used in combination with either a semi-occlusive or non-occlusive secondary dressing
  • Prior to application in dry wounds saline solution should be used to hydrate Promogran Prisma
  • Before application, necrotic tissue must first be removed by debridement
  • Prepare the wound according to appropriate wound management protocol

Prisma Dressing Instructions For Use:

  • For optimal effect, apply Promogran Prisma Matrix Wound Dressing directly to the whole wound bed.
  • For a wound with low or no exudate apply Prisma Wound Dressing and hydrate with saline solution. This will initiate the transformation of the Promogran Prisma Matrix into a gel.
  • After hydration, the Promogran Prisma gel will come in contact with the wound surface.
  • The biodegradable Promogran Prisma Matrix gel is naturally absorbed into the body over time.
  • In order to maintain a moist wound healing environment Promogran Prisma Dressing must be covered with a semi-occlusive dressing (e.g. Bioclusive Transparent Dressing, Tielle or Tielle Plus Hydropolymer Dressings) or a non-occlusive secondary dressing and fixed to the skin with a non-irritating tape.
  • After initial application, reapply Prisma Collagen Dressing to the wound daily as per physician recommendation.
  • It is not necessary to remove any residual of Prisma Dressing during dressing changes.

  • Promogran Prisma Wound Dressing User Guide


  • Only when proper medical treatment addresses the underlying cause, the Promogran Prisma Dressing may be used when visible signs of infection are present in the wound
  • Not intended to be a substitute for appropriate treatment of infection
  • Healthcare professionals/clinicians should be aware of the fact that there is very limited data available on prolonged and repeated use of silver containing dressings, particularly in children and neonates

Storage Instructions:

  • Promogran Prisma Matrix Wound Dressing should be stored away from direct light
  • Over-exposure to light may cause some discoloration, however this does not affect the release of silver from the dressing
  • Store below 25 degrees C / 77 degrees F

Customer Reviews

Questions & Answers

can it be used in conjunction w/ a wound vac?
Karla - 9/20/2015 8:53:45 PM
Thank you for reaching out to us. 

I have spoke with KCI (formerly Systagenix Wound Management) who is the manufacturer of the product. The product you mentioned is NOT recommended for use with Vac Therapy (WoundVac).

Per the clinical nurse, the product becomes gelatinous when moist and therefore can be sucked through the tubing of the Vac limiting its effectiveness if not causing a malfunction altogether. They do not have any dressings specifically recommended for the proposed use. 

Feel free to contact them directly at 1-800-275-4524 ext 56650.
Customer Service - 9/22/2015 1:47:08 AM
How often should dressing be changed?
Sharon - 4/12/2015 5:47:39 PM
Thank you for reaching out to us. The interval between dressing changes is determined principally by the condition of the wound. In heavily exuding wounds, it may be necessary to replace the matrix daily initially, but on lightly exuding wounds it may be left undisturbed for 2 to 3 days.
Customer Care - 4/13/2015 5:46:44 AM
When is treatment contraindicated?
Jim - 10/7/2014 12:31:26 AM
Neither product should be used on patients with full-thickness burn injuries, active vasculitis or a known hypersensitivity to either collagen or ORC. If infection is present or suspected, it should be treated according to local policy. Promogran Prisma can be used with systemic antibiotics to treat infection.
Customer Care - 12/27/2014 2:15:33 AM
When should treatment be discontinued?
Jessica - 10/6/2014 12:36:54 AM
There is no need to stop Promogran Prisma if the wound is progressing well. However, if the wound is epithelialising and there is no exudate, it may be more appropriate to change to a simple non-adherent dressing.
Customer Care - 10/7/2014 12:12:01 AM
What factors indicate this is the right dressing choice?
Billie - 10/2/2014 7:56:54 AM
During the first few dressing changes there should be a change in the colour of the wound bed and a reduction in the amount of sloughy tissue present. Following two weeks of treatment there should be a marked reduction in the level of exudate. Often the first change is that patients report a reduction in the level of pain experienced.
Customer Care - 10/3/2014 12:19:31 AM
Can it be used under compression bandage?
Iracema - 9/29/2014 7:49:09 AM
It can be used under compression bandaging and does not cause indentation, skin irritation or maceration, even when the dressing is overlapped at the wound edge.
Customer Care - 10/1/2014 12:23:45 AM
What is the frequency of change?
Henry - 9/19/2014 8:01:54 AM
  • Based on instructions of use, the dressing should be changed every 72 hours or more frequently if the exudate level is high.
  • If the gel has not biodegraded the dressing should be left in place until the next dressing change, minimising disturbance to the wound.
  • If there is no residue of gel in the wound bed or traces left on the secondary dressing and the wound bed is clean and granulating, the dressing has fully biodegraded.
Customer Care - 9/20/2014 12:15:59 AM
How do I use it?
David - 9/13/2014 7:53:16 AM
  • Prepare the wound bed - removal of necrotic or sloughy tissue and any previous dressings.
  • Assess the level of exudates - a small amount of saline can be added to the surface of the dressing once it has been applied to the wound bed. This helps to initiate the breakdown of the dressing and its ability to modify the wound environment.
  • Apply the dressing - Place the dressing in the wound bed. If the patient has multiple small wounds the dressing can be broken into smaller pieces with a gloved hand.
  • Dressing review – Based on instructions of use, the dressing should be changed every 72 hours or more frequently if the exudate level is high.
Customer Care - 9/15/2014 12:30:06 AM
When do I use Promogran Prisma?
Kathleen - 9/5/2014 7:38:12 AM
PROMOGRAN PRISMA Matrix is indicated for the management of all wounds healing by secondary intent which are clear of necrotic tissue including:
  • Diabetic ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular aetiologies
  • Traumatic wounds and surgical wounds It has known haemostatic properties and can be used under compression therapy.
Customer Care - 9/6/2014 12:22:57 AM
What is the role of collagen in tissue repair?
Anna - 8/13/2014 12:27:30 AM
  • Helps to stop bleeding (haemostatic properties)
  • Has a low-inflammatory and low-antigenic response, which does not cause an adverse reaction (even when collagen from different species is used)
  • Enhances the deposition of new collagen and reduces wound contraction
  • Collagen fragments (peptides – formed on degradation of the dressing) can attract cells into the wound area (chemotaxis) and induce cell growth (cell proliferation)
  • Collagen peptides break down to amino acids, which can be reused by the cells to help build new proteins
  • Reduces MMP activity, an effect that helps control the proteolytic environment in the chronic wound
Customer Care - 8/14/2014 12:10:29 AM
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