Ethicon Dermabond Advanced Topical Skin Adhesive
Ethicon Dermabond Advanced Topical Skin Adhesive

Ethicon Dermabond Advanced Topical Skin Adhesive

Dermabond Advanced Topical Skin Adhesive is intended for topical application only, to hold closed easily approximated skin edges of wounds from surgical incisions, including incisions from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations. It can be used in conjunction with, but not in place of, deep dermal stitches. Dermabond Advanced Topical Skin Adhesive is a wound closure device that adds strength when used in conjunction with deep dermal stitches after strength, provides a protective barrier and demonstrated in vitro inhibits bacteria. 

Dermabond Advanced Topical Skin Adhesive Highlights:

  • Add 75% more strength to wound closure
  • Microbial barrier protection
  • Optimize surgeon experience
  • Embedded initiator technology to avoid clogging
  • Controlled edge design
  • Faster drying time
  • Advanced silicone technology

Item #DescPkgRewardPrice 
DNX12 0.7mL Each $1.92
$84.99
$63.99
DNX12 0.7mL 12/Pack $22.68
$999.99
$755.99

Dermabond Advanced Topical Skin Adhesive Features

  • Sterile, liquid topical skin adhesive containing a monomeric (2-octyl cyanoacrylate) formulation and the colorant D & C Violet No. 2
  • It is provided as a single use applicator in a blister package
  • The pen style applicator is composed of a crushable ampoule contained within a plastic applicator
  • As it is applied to the skin, the liquid is syrup-like in viscosity and polymerizes within minutes
  • Acts as a barrier to prevent microbial penetration as long as the adhesive remains
  • When used with sutures, Dermabond Advanced was shown ex vivo to add 75% more strength to the wound closure than sutures alone
  • Pen style applicator consists of a crushable ampoule contained within a plastic applicator
  • Adhesive will slough off usually within 5 to 10 days
  • Supplied in a blister package to maintain the sterility of the device until opened or damaged
  • Active Ingredient: 2-Octyl Cyanoacrylate
  • 0.7 mL formulation to close wounds up to 15 cm
  • Faster drying time in a single layer application
  • Cutting edge design for controlled fine and wide line application
  • Advanced silicone technology for easy activation and expression of adhesive
  • Provides a microbial barrier with 99% protection in vitro for at least 72 hours against organisms commonly responsible for surgical site infections 

Ethicon Dermabond Advanced Topical Skin Adhesive User Manual

How to Use Dermabond Topical Skin Adhesive?

  • The application of Dermabond Advanced Adhesive requires thorough wound cleansing. Follow standard surgical practice for wound preparation before application of Dermabond Advanced Adhesive (i.e., anesthetize, irrigate, debride, ensure hemostasis, and close deep layers making sure that the wound edges can be easily approximated).
  • Pat the wound dry with dry, sterile gauze to ensure direct contact of the Dermabond Advanced Adhesive to the skin. Moisture accelerates Dermabond Advanced Adhesive’s polymerization and may affect wound closure results. 
  • To prevent inadvertent flow of liquid Dermabond Advanced Adhesive to unintended areas of the body, the wound should be maintained in a horizontal position and the Dermabond Advanced Adhesive should be applied from above the wound. 
  • Dermabond Advanced Adhesive should be used immediately after crushing the ampoule, since the liquid Dermabond Advanced Adhesive will flow freely from the tip for only a few minutes. 
  • Refer to the instructions on the package for crushing the ampoule and expressing the liquid adhesive. Remove the applicator from the blister package. Hold the applicator with the thumb and a finger away from the patient to prevent any unintentional placement of the liquid Dermabond Advanced Adhesive into the wound or on the patient. With the applicator tip pointing downward, apply pressure at the midpoint of the bulb to crush the ampoule. Gently squeeze the applicator sufficiently to moisten the internal filter with the liquid adhesive. Stop squeezing and allow the liquid Dermabond Advanced Adhesive to draw back into the applicator. 
  • Approximate the wound edges with gloved fingers or sterile forceps. Slowly apply the liquid Dermabond Advanced Adhesive in one continuous layer to the surface of the approximated wound edges using a gentle brushing motion. Maintain manual approximation of the wound edges for approximately 60 seconds after the application. The width of the layer can be increased or decreased by adjusting the amount of pressure applied to the bulb during application. NOTE: Dermabond Advanced Adhesive polymerizes through an exothermic reaction in which a small amount of heat is released. Dermabond Advanced Adhesive is to be applied in one continuous layer. Applying Dermabond Advanced Adhesive in one continuous layer onto a dry wound will minimize the sensation of heat. Applying a second layer is not required or recommended. If a second layer of Dermabond Advanced Adhesive is applied or if large droplets of liquid are not spread thinly, the patient may experience an increased sensation of heat or discomfort. Avoid excessive pressure of the applicator tip against the wound edges or surrounding skin to avoid forcing the wound edges apart and allowing Dermabond Advanced Adhesive into the wound. Full apposition strength is expected to be achieved within minutes after the adhesive is applied. Full polymerization is expected when the Dermabond Advanced Adhesive layer is no longer sticky.
  • Do not apply liquid or ointment medications onto wounds closed with Dermabond Advanced Adhesive because these substances can weaken the polymerized film, leading to dehiscence (skin edge separation). 
  • Protective dry dressings such as gauze may be applied only after Dermabond Advanced Adhesive film is completely polymerized: not tacky to the touch after a few minutes. Allow the Dermabond Advanced Adhesive to fully polymerize before applying a bandage.
  • Patients should be instructed to not pick at the polymerized film of Dermabond Advanced Adhesive. Picking at the film can disrupt its adhesion to the skin and cause dehiscence (skin edge separation). 
  • Patients should be instructed that until the polymerized film of Dermabond Advanced Adhesive has sloughed naturally (usually in 5–10 days), there should be only transient wetting of the treatment site. Patients may immediately shower or bathe the site gently as directed by their physician. The site should not be scrubbed, soaked, or exposed to prolonged wetness until after the film has sloughed naturally and the physician has determined that the wound is adequately healed. Patients should be instructed not to swim during this period. 
  • If removal of Dermabond Advanced Adhesive is necessary for any reason, carefully apply petroleum jelly or acetone to the Dermabond Advanced Adhesive film to help loosen the bond. Peel off the film; do not pull the skin edges apart.

When to Use Dermabond Advanced Adhesive?

  • Dermabond Advanced Adhesive is intended for topical application only, to hold closed easily approximated skin edges of wounds from surgical incisions, including incisions from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations. Dermabond Advanced Adhesive may be used in conjunction with, but not in place of, deep dermal stitches.


Storage Instructions:

  • Recommended storage conditions: below 30°C, 86°F, away from moisture, direct heat, and direct light. Do not use after expiry date.


Contraindications:

  • Do not use on any wound with evidence of active infection, gangrene, or wounds of decubitus etiology.
  • Do not use on mucosal surfaces or across mucocutaneous junctions (e.g., oral cavity, lips), or on skin which may be regularly exposed to body fluids or with dense natural hair (e.g. scalp).
  • Do not use on patients with a known hypersensitivity to cyanoacrylate, formaldehyde, or benzalkonium chloride.


Precautions

  • Do not apply liquid or ointment medications or other substances to the wound after closure with Dermabond Advanced Adhesive, as these substances can weaken the polymerized film and allow for dehiscence (skin edge separation). Prior to application, cleanse the application site thoroughly to remove any remaining blood, fluids or topical medications/anesthetics.
  • Dermabond Advanced Adhesive, as a liquid, is syrup-like in viscosity. To prevent inadvertent flow of liquid Dermabond Advanced Adhesive to unintended areas, the wound should be maintained in a horizontal position, with Dermabond Advanced Adhesive applied from above.
  • Hold applicator away from yourself and the patient with the tip pointing down and break the ampoule close to the center of the bulb one time only. Do not crush the contents of the applicator repeatedly as further manipulation of the applicator may cause glass shard penetration of the outer tube. Glass shard penetration can result in inadvertent skin punctures, which may result in the transmission of bloodborne pathogens.
  • Dermabond Advanced Adhesive should be used immediately after crushing the ampoule because the adhesive will polymerize in the applicator, rendering the device unusable.
  • If unintended bonding of intact skin occurs, peel the adhesive from the skin, but do not pull the skin edges apart. Petroleum jelly or acetone may help loosen the bond. Other agents such as water, saline, or soap are not expected to immediately loosen the bond.

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