Smith & Nephew Iodosorb Cadexomer Iodine Gel

How to use Smith & Nephew Iodosorb Cadexomer Iodine Gel

1. Open the tube and squeeze gel on to non-adherent gauze to the shape of the ulcer and to a depth of 3 to 4 mm.
2. Position the Iodosorb gel face of the gauze on the wound surface and apply mild pressure to fix in place.
3. Gently take off the existing dressing which should be moistened with saline if it is tending to adhere to the wound surface.
4. Remove any remaining Iodosorb with a gentle stream of saline or sterile water if applicable.
5. Gently blot away any excess fluid before re-applying Iodosorb wound dressing.

How does Cadexomer Iodine work?

Cadexomer Iodine is a uniquely formulated starch matrix formed into spherical, highly absorbent microbeads containing 0.9% elemental iodine. The Cadexomer is a 3D cross - linked polysaccharide starch matrix. The 0.9% iodine is physically bound to the Cadexomer matrix and is only released when it is required. Wound fluid and exudate are absorbed into the Cadexomer beads of the Cadexomer Iodine, allowing the iodine to be released slowly.

When Cadexomer Iodine is applied to the wound surface, exudate, pus and debris are absorbed into the Cadexomer beads. The beads will swell resulting in the formation of a demonstrable gel. The presence of exudate and the consequent swelling of the beads results in the cross-linked bonds of the Cadexomer matrix breaking and the iodine being released into the surrounding wound environment.

When the iodine is released, the amount of iodine released will be to a level such that the concentration of iodine in the dressing and the wound environment reach equilibrium. The equilibrium will remain and no further iodine will be released until the balance is disturbed. Once the iodine in the surrounding wound environment has been depleted, more will be released from the product until the equilibrium is reached again and will remain until disturbed. This process will continue until all the 0.9% iodine within the product has been exhausted.

When to use Iodosorb Cadexomer Iodine Gel

The indications for Smith & Nephew Iodosorb Gel include the treatment of infected wounds, such as:

• Treating wet ulcers
• Venous Stasis Ulcers
• Pressure sores
• Diabetic foot ulcers
• Infected, traumatic, and surgical wounds

When not to use Iodosorb Cadexomer Iodine Gel?

• Iodine sensitivity
• Hashimotos thyroiditis
• Non-toxic nodular goiter
• Graves Disease
• Pregnant or lactating women

Precautions to take while using Iodosorb Wound Gel:

• As Iodosorb Gel contains 0.9% w/w iodine it should not be used in patients with known or suspected Iodine sensitivity
• Iodosorb Gel is contraindicated in Hashimoto Thyroiditis
• In patients with a prior history of Graves Disease it is not recommended to use iodine containing products, which includes Iodosorb Gel
• The gel should not be used in the case of non-toxic nodular goitre
• Patients with a past history of any thyroid disorder are more susceptible to alteration in thyroid metabolism with chronic Iodosorb therapy
• In endemic goiter, there have been isolated reports of hyperthyroidism associated with Iodosorb
• There is a potential for interaction of iodine with the following drugs and therefore co-administration is not recommended, Lithium, Sulphafurazoles and Sulphonylureas
• It has been observed occasionally that an adherent crust can form when the dressing is not changed with significant frequency
• Iodine can cross the placental barrier and is secreted into milk
• Do not use Iodosorb in pregnant or lactating women

What Benefits of Iodosorb Cadexomer Iodine Gel?

• Antimicrobial Properties: The smart release system of Cadexomer Iodine allows Iodosorb to provide sustained antimicrobial activity for up to 72 hours. Iodine has a broad antimicrobial spectrum and a short kill time at low concentrations. Not only does iodine kill a broad spectrum of microorganisms, it does so very rapidly.

• Odor Control: Odor is generated by wounds which are infected and heavily colonized by anaerobic and aerobic bacteria. Odor is attributed to the volatiles produced by the bacteria within a wound. Therefore, control of such bacteria also controls the associated odor.

• Desloughing Properties: Wound fluid, containing bacteria and cellular debris is readily drawn up into the Cadexomer matrix. This cleans the wound bed of extra debris and bacteria, thereby promoting wound healing. Desloughing and removal of bacteria from wound is believed to be responsible for the increase in wound healing and the rate of epithelialization.

• Exudate Control Properties: Cadexomer Iodine manages excess exudate by its ability to absorb up to six times its own weight. This reduces the risk of maceration and leakage. It can result in less dressing changes and reduced nursing supervision for patients compared to standard wound management modalities.

• Cadexomer Iodine Safety: Iodosorb has a concentration of 0.9% Cadexomer Iodine and studies show that at this concentration and complexed to cadexomer, there is no evidence that Iodosorb is toxic. Moreover, the concentration gradient of iodine is formed with the lowest concentration at the wound surface and the greatest concentration away from the wound.

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